Items where Subject is "B000 Health Professions > B200 Pharmacology Toxicology and Pharmacy"

A

Adu, J., Leong, F.T., Smith, N., Leek, J.P., Markham, A.F., Robinson, P.A. and Mighell, A.J. (2002) Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development Mechanisms of development, 119 (Supplement 1). pp. 43-47. ISSN 0925-4773

Araim, Z., Ingram, M.J., Moss, G.P., Patel, B., Santin, M. and Meikle, S.T. (2010) Synthesis of NO-releasing peptides and peptoids for stent coating Journal of Pharmacy and Pharmacology, 62 (10). p. 1381. ISSN 0022-3573

Arimoto-Kobayashi, S., Ando, Y., Horai, Y., Okamoto, K., Hayatsu, H., Lowe, J.E. and Green, M.H.L. (2002) Mutation, DNA strand cleavage and nitric oxide formation caused by N-nitrosoproline with sunlight: a possible mechanism of UVA carcinogenicity Carcinogenesis, 23 (9). pp. 1537-1540. ISSN 1460-2180

B

Beeharry, N., Chambers, J.A. and Green, I.C. (2004) Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition Apoptosis, 9 (5). pp. 599-607. ISSN 1573-675X

Burton, D.G.A., Allen, M.C., Bird, J.L.E. and Faragher, R.G.A. (2005) Bridging the gap: ageing, pharmacokinetics and pharmacodynamics Journal of pharmacy and pharmacology, 57 (6). pp. 671-680. ISSN 0022-3573

C

Chatterjee, P.K. (2005) Pleiotropic renal actions of erythropoietin Lancet, 365 (9474). pp. 1890-1892. ISSN 0140-6736

Chatterjee, P.K. (2004) Water-soluble carbon monoxide-releasing molecules: helping to elucidate the vascular activity of the 'silent killer' British journal of pharmacology, 142 (3). pp. 391-393. ISSN 0007-1188

Chatterjee, P.K., Brown, P.A.J., Cuzzocrea, S., Zacharowski, K., Stewart, K.N., Mota-Filipe, H., McDonald, M.C. and Thiemermann, C. (2001) Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat Kidney international, 59 (6). pp. 2073-2083. ISSN 1530-6860

Chatterjee, P.K., Todorovic, Z., Sivarajah, A., Mota-Filipe, H., Brown, P.A.J., Stewart, K.N., Mazzon, E., Cuzzocrea, S. and Thiemermann, C. (2005) Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury Biochemical Pharmacology, 69 (7). pp. 1121-1131. ISSN 0006-2952

Chika , A., Gard, P.R., Ingram, M.J. and Moss, G.P. (2010) Synthesis and ACE-inhibitory potency of captopril branched chain ester prodrugs Journal of Pharmacy and Pharmacology, 62 (10). pp. 1374-1375. ISSN 0022-3573

Cohen, J., Gard, P.R., Haq, I. and Llewelyn, M. (2009) An academia-industry partnership The Lancet, 374 (9693). p. 880. ISSN 0140-6736

Conroy, S.J., Green, I.C., Dixon, G., Byrne, P.M., Nolan, J., Abdel-Wahab, Y.H.A., McClenaghan, N., Flatt, P.R. and Newsholme, P. (2002) Evidence for a sustained increase in clonal beta-cell basal intracellular Ca2+ levels after incubation in the presence of newly diagnosed Type-1 diabetic patient sera. Possible role in serum-induced inhibition of insulin secretion Journal of endocrinology, 173 (1). pp. 53-62. ISSN 1479-6805

Cuzzocrea, S., Chatterjee, P.K., Mazzon, E., Dugo, L., De Sarro, A., Van de Loo, F.A.J., Caputi, A.P. and Thiemermann, C. (2002) Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury Shock, 18 (2). pp. 169-176. ISSN 1073-2322

Cuzzocrea, S., Chatterjee, P.K., Mazzon, E., Serraino, I., Dugo, L., Centorrino, T., Barbera, A., Ciccolo, A., Fulia, F., McDonald, M.C., Caputi, A.P. and Thiemermann, C. (2002) Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat* Critical Care Medicine, 30 (10). pp. 2284-2294. ISSN 1530-0293

Cuzzocrea, S., Pisano, B., Dugo, L., Ianaro, A., Patel, N.S.A., Di Paola, R., Genovese, T., Chatterjee, P.K., Fulia, F., Cuzzocrea, E., Di Rosa, M., Caputi, A.P. and Thiemermann, C. (2004) Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-[gamma], reduces the development of nonseptic shock induced by zymosan in mice Critical Care Medicine, 32 (2). pp. 457-466. ISSN 0090-3493

Cuzzocrea, S., Wayman, N.S., Mazzon, E., Dugo, L., Di Paola, R., Serraino, I., Britti, D., Chatterjee, P.K., Caputi, A.P. and Thiemermann, C. (2002) The Cyclopentenone Prostaglandin 15-Deoxy-Delta 12,14-Prostaglandin J2 attenuates the development of acute and chronic inflammation Molecular pharmacology, 61 (5). pp. 997-1007. ISSN 0026-895X

D

Demaegdt, H., Gard, P.R., De Backer, J-P., Lukaszuk, A., Szemenyei, E., Toth, G., Tourwe, D. and Vauquelin, G. (2011) Binding of AT4 receptor ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells Molecular and Cellular Endocrinology, 339 (1-2). pp. 34-44. ISSN 0303-7207

Dick, G.M., Hunter, A.C. and Sanders, K.M. (2002) Ethylbromide Tamoxifen, a membrane-impermeant antiestrogen, activates smooth muscle calcium-activated large-conductance Potassium channels from the extracellular side Molecular pharmacology, 61 (5). pp. 1105-1113. ISSN 1521-0111

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Evgenov, O.V., Pacher, P., Williams, W., Evgenov, N.V., Mabley, J.G., Cicila, J., Siko, J.B., Salzman, A.L. and Szabo, C. (2003) Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats Critical care medicine, 31 (10). pp. 2429-2436. ISSN 1530-0293

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Gard, P.R. (2005) The brain renin-angiotensin system: a target for novel antidepressants and anxiolytics Drug development research, 65 (4). pp. 270-277. ISSN 0272-4391

Gard, P.R. (2008) Cognitive-enhancing effects of angiotensin IV BMC Neuroscience, 9 (S2). S15. ISSN 1471-2202

Gard, P.R. (2010) Non-adherence to antihypertensive medication and impaired cognition: which comes first? International Journal of Pharmacy Practice , 18 (5). pp. 252-259. ISSN 0961-7671

Gard, P.R. (2002) The role of angiotensin II in cognition and behaviour European journal of pharmacology, 438 (1-2). pp. 1-14. ISSN 0014-2999

Gard, P.R., Haigh, S.J., Cambursano, P.T. and Warrington, C.A. (2001) Strain differences in the anxiolytic effects of losartan in the mouse Pharmacology biochemistry and behavior, 69 (1-2). pp. 35-40. ISSN 0091-3057

Gard, P.R., Naylor, C., Sofiya, A. and Partington, C. (2012) Blockade of pro-cognitive effects of angiotensin IV and physostigmine in mice by oxytocin antagonism European Journal of Pharmacology, 683 . pp. 155-160. ISSN 0014-2999

GARD, PAUL (2010) Implications of the angiotensin converting enzyme gene insertion/deletion polymorphism in health and disease: a snapshot review International Journal of Molecular Epidemiology and Genetics, IJMEG, 1 (2). pp. 145-147. ISSN 1948-1756

Golding, B.J., OVERALL, ANDREW and GARD, PAUL (2011) Strain differences and the role of AT1 receptor expression in anxiety International Journal of Molecular Epidemiology and Genetics, IJMEG, 2 (1). pp. 51-55. ISSN 1948-1756

Golding, Bruno J. D., Overall, A.D.J., Brown, Graham and Gard, P.R. (2010) Strain differences in the effects of Angiotensin IV on mouse cognition European Journal of Pharmacology, 641 (2-3). pp. 154-159. ISSN 0014-2999

Gullick, Darren R., Pugh, W.J., Ingram, M.J., Cox, P.A. and Moss, Gary P. (2010) Formulation and characterization of a captopril ethyl ester drug-in-adhesive-type patch for percutaneous absorption Drug Development and Industrial Pharmacy, 36 (8). pp. 926-932. ISSN 0363-9045

Gupta, K. and Horne, R. (2001) The influence of health beliefs on the presentation and consultation outcome in patients with chemical sensitivities Journal of psychosomatic research, 50 (3). pp. 131-137. ISSN 0022-3999

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Hallam, M.J., Allen, J.M., JAMES, S.Elizabeth, Donaldson, P.M.W., Davies, J.G., HANLON, GEOFF and Dheansa, B. (2010) Potential sub-theraputic linezolid and meropenem antibiotic concentrations in a patient with severe burns and sepsis Journal of Burn Care and Research, 31 (1). pp. 207-209. ISSN 1559-047X

Hasko, G., Mabley, J.G., Nemeth, Z.H., Pacher, P., Deitch, E.A. and Szabo, C. (2002) Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation Molecular Medicine, 8 (5). pp. 283-289. ISSN 1076-1551

Heikal, A., Box, K., Rothnie, A., Storm, J., Callaghan, R. and Allen, M.C. (2009) The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides Cryobiology, 58 (1). pp. 37-44. ISSN 0011-2240

Helyar, Simon G., Patel, Bella, Headington, Kevin, El Assal, Mary, Chatterjee, Prabal K., Pacher, Pal and Mabley, J.G. (2009) PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase Biochemical Pharmacology, 78 (8). pp. 959-965. ISSN 0006-2952

Herson, K., Sosabowski, M.H. and Lloyd, A.W. (2000) Case Studies in Networked Distance-based Learning Technologies in Pharmacy Education In: Bourner, T. and Katz, T., eds. New Directions for Professional Education in Universities. Open University Press/Society for Research into Higher Education, Buckingham. ISBN 0-335-20614-X

Hunter, A.C. and Moghimi, S.M. (2003) Synthetic polymers in 21st century therapeutics: the way forward Drug discovery today, 8 (4). pp. 154-156. ISSN 1359-6446

Hunter, A.C. and Moghimi, S.M. (2002) Therapeutic synthetic polymers: a game of Russian roulette? Drug discovery today, 7 (19). pp. 998-1001. ISSN 1359-6446

I

Ingram, M.J., Edmonds, H., Moss, G., Long, A.J., Sosabowski, M.H. and McLennan, M.W. (2004) The role of handouts in the MPharm degree pathway - differentiating between the inquisitive and the acquisitive Pharmacy Education, 4 (1). pp. 7-12. ISSN 1560-2214

Ingram, M.J., Moynihan, H.A., Powell, M.W. and Rostron, C. (2001) Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3-nitrate, a putative pro-drug of ibuprofen and glycerol-1-nitrate Journal of Pharmacy and Pharmacology, 53 (3). pp. 345-350. ISSN 0022-3573

Ingram, M.J., Sagoe, L.A., Moss, G., Long, A.J. and Sosabowski, M.H. (2007) Pharmacy student perceptions of educational media tools Pharmacy Education, 7 (1). pp. 77-82. ISSN 1560-2214

J

Jackson, A., Duka, T. and Stephens, D.N. (2003) Effects of alcohol and Lorazepam during extinction of alcohol self-administration in rats Journal of Psychopharmacology, 17 (3). pp. 293-299.

Jackson, A., Stephens, D.N. and Duka, T. (2005) Gender differences in response to lorazepam in a human drug discrimination study Journal of Psychopharmacology, 19 (6). pp. 614-619. ISSN 0269-8811

Jagtap, P., Soriano, F.G., Virag, L., Liaudet, L., Mabley, J.G., Szabo, E., Hasko, G., Marton, A., Lorigados, C.B., Gallyas, F., Sumegi, B., Hoyt, D.G., Baloglu, E., VanDuzer, J.H., Salzman, A.L., Southan, G.J. and Szabo, C. (2002) Novel phenanthridinone inhibitors of poly(adenosine 5'-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents* Critical Care Medicine, 30 (5). pp. 1071-1082. ISSN 0090-3493

Jagtap, P., Southan, G.J., Baloglu, E., Ram, E., Mabley, J.G., Marton, A., Salzman, A.L. and Szabo, C. (2004) The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) Bioorganic & medicinal chemistry letters, 14 . pp. 81-85. ISSN 0960-894X

K

Katsoulieris, Elias, Mabley, J.G., Samai, M., Green, Irene C. and Chatterjee, Prabal K. (2009) Alpha-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress European Journal of Pharmacology, 623 (1-3). pp. 107-112. ISSN 0014-2999

Kockisch, S., Rees, G.D., Young, S.A., Tsibouklis, J. and Smart, J.D. (2001) A direct-staining method to evaluate the mucoadhesion of polymers from aqueous dispersion Journal of Controlled Release, 77 (1-2). pp. 1-6.

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Lakey, J.R.T., Suariz-Pinzon, W.L., Strynadka, K., Korbutt, G.S., Rajotte, R., Mabley, J.G., Szabo, C. and Rabinovitch, A. (2001) Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells Laboratory Investigation, 81 (12). pp. 1683-1692. ISSN 0023-6837

Liaudet, L., Deb, A., Pacher, P., Mabley, J.G., Murthy, K.G.K., Salzman, A.L. and Szabo, C. (2002) The flagellin-TLR5 axis: therapeutic opportunities Drug news and perspectives, 15 (7). pp. 397-409. ISSN 0214-0934

Liaudet, L., Mabley, J.G., Pacher, P., Virag, L., Soriano, F.G., Marton, A., Hasko, G., Deitch, E.A. and Szabo, C. (2002) Inosine exerts a broad range of antiinflammatory effects in a hurine model of acute lung injury Annals of Surgery, 235 (4). pp. 568-578. ISSN 1528-1140

Liaudet, L., Szabo, C., Evgenov, O.V., Murthy, K.G.K., Pacher, P., Virag, L., Mabley, J.G., Marton, A., Soriano, F.G., Kirov, M.Y., Bjertnaes, L.J. and Salzman, A.L. (2003) Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis Shock, 19 (2). pp. 131-137. ISSN 1073-2322

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Mabley, J.G., Horvath, E.M., Murthy, K.G.K., Zsengeller, Z., Vaslin, A., Benko, R., Kollai, M. and Szabo, C. (2005) Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation Journal of pharmacology and experimental therapeutics, 315 . pp. 812-820. ISSN 1521-0103

Mabley, J.G., Pacher, P., Southan, G.J., Salzman, A.L. and Szabo, C. (2002) Nicotine reduces the incidence of type I diabetes in mice Journal of Pharmacology and Experimental Therapeutics, 300 (3). pp. 876-881. ISSN 1521-0103

Mabley, J.G., Rabinovitch, A., Suarez-Pinzon, W.L., Hasko, G., Pacher, P., Power, R., Southan, G.J., Salzman, A.L. and Szabo, C. (2003) Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes Molecular medicine, 9 (3-4). pp. 96-104. ISSN 1076-1551

Mabley, J.G., Soriano, F.G., Pacher, P., Hasko, G., Marton, A., Wallace, R., Salzman, A.L. and Szabo, C. (2003) The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, is protective in two murine models of colitis European journal of pharmacology, 466 (3). pp. 323-329. ISSN 0014-2999

McDonald, M.C., Mota-Filipe, M., Paul, A., Cuzzocrea, S., Abdelrahman, M., Harwood, S., Plevin, R., Chatterjee, P.K., Yaqoob, M.M. and Thiemermann, C. (2001) Calpain inhibitor I reduces the activation of nuclear factor-{kappa}B and organ injury/dysfunction in hemorrhagic shock Faseb journal, 15 . pp. 171-186. ISSN 1530-6860

McKenzie, Catherine A., McKinnon, William, Naughton, D.P., Treacher, David, Davies, Graham, Phillips, G.J. and Hilton, Philip J. (2004) Differentiating midazolam over-sedation from neurological damage in the intensive care unit Critical care, 9 (1). R32-R36. ISSN 1466-609X

Mechaeil, R., Gard, P.R., Jackson, A. and Rusted, J. (2011) Cognitive enhancement following acute losartan in normotensive young adults Psychopharmacology, 217 (1). pp. 51-60. ISSN 0033-3158

Melillo, M., Gun'ko, V.M., Tennison, S.R., Mikhalovska, L.I., Phillips, G.J., Davies, Graham, Lloyd, A.W., Kozynchenko, O.P., Malik, D.J., Streat, M. and Mikhalovsky, S.V. (2004) Structural characteristics of activated carbons and ibuprofen adsorption affected by bovine serum albumin Langmuir, 20 (7). pp. 2837-2851. ISSN 1520-5827

Melillo, M., Phillips, G.J., Davies, Graham, Lloyd, A.W., Tennison, S.R., Kozynchenko, O.P. and Mikhalovsky, S.V. (2004) The effect of protein binding on ibuprofen adsorption to activated carbons Carbon, 42 (3). pp. 565-571. ISSN 0008-6223

Murakami, K., Enkhbaatar, P., Shimoda, K., Cox, R.A., Burke, A.S., Hawkins, H.K., Traber, L.D., Schmalstieg, F.C., Salzman, A.L., Mabley, J.G., Komjati, K., Pacher, P., Zsengeller, Z., Szabo, C. and Traber, D.L. (2004) Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis Shock, 21 (2). pp. 126-133. ISSN 1073-2322

N

Naseem, A., Olliff, C.J., Martini, L.G. and Lloyd, A.W. (2004) Effects of plasma irradiation on the wettability and dissolution of compacts of griseofulvin International journal of pharmaceutics, 269 (2). pp. 443-450. ISSN 0378-5173

Nesic, J., Duka, T., Rusted, J.M. and Jackson, A. (2011) A role for glutamate in subjective response to smoking and its action on inhibitory control Psychopharmacology, 216 . pp. 29-42. ISSN 0033-3158

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Ostler, E.L., Resmini, M., Brocklehurst, K. and Gallacher, G. (2002) Polyclonal catalytic antibodies Journal of immunological methods, 269 (1-2). pp. 111-124. ISSN 0022-1759

P

Pacher, P., Cziraki, A., Mabley, J.G., Liaudet, L., Papp, L and Szabo, C. (2002) Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents Biochemical pharmacology, 64 (12). pp. 1785-1791. ISSN 0006-2952

Patel, N.S.A., Cuzzocrea, S., Chatterjee, P.K., Di Paola, R., Sautebin, L., Britti, D. and Thiemermann, C. (2004) Reduction of renal Ischemia-Reperfusion Injury in 5-Lipoxygenase knockout mice and by the 5-Lipoxygenase inhibitor Zileuton Molecular pharmacology, 66 (2). pp. 220-227. ISSN 0026-895X

S

Saab, Y.B, Gard, P.R and Overall, A.D.J (2007) The geographic distribution of the ACE II genotype: a novel finding Genetics Research, 89 (4). pp. 259-267. ISSN 0016-6723

Saab , Y.B., Gard , P.R. and Overall, A.D.J. (2011) The association of hypertension with renin-angiotensin system gene polymorphisms in the Lebanese population Journal of the Renin-Angiotensin-Aldosterone System, 12 (7). pp. 588-594. ISSN 1470-3203

Salvage, J.P., Rose, S.F., Phillips, G.J., Hanlon, G.W., Lloyd, A.W., Ma, I.Y., Armes, S.P., Billingham, N.C. and Lewis, A.L. (2005) Novel biocompatible phosphorylcholine-based self-assembled nanoparticles for drug delivery Journal of controlled release, 104 (2). pp. 259-270. ISSN 0168-3659

Soriano, F.G., Liaudet, L., Szabo, E., Virag, L., Mabley, J.G., Pacher, P. and Szabo, C. (2002) Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice Shock, 17 (4). pp. 286-292. ISSN 1073-2322

Sosabowski, M.H. (2004) Review of Clarke's analysis of drugs and poisons, 3rd ed. Pharmacy Education . ISSN 1560-2214

Sosabowski, M.H., Olivier, G.W.J., Bratt, A., Sawers, R., Zahoui, A-M. and Denyer, S.P. (2003) Enhancing quality in the M.Pharm degree programme - optimisation of the personal tutor system Pharmacy Education, 3 (2). pp. 103-108. ISSN 1560-2214

Stickings, P. and Cunningham, J.M. (2002) Interleukin 1β- induced nitric oxide production and inhibition of insulin secretion in rat islets of Langerhans is dependent upon the nitric oxide synthase cofactor tetrahydrobiopterin Cytokine, 18 (2). pp. 81-85. ISSN 1096-0023

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Todorovic, Zoran, Nesic, Zorica, Stojanovic, Radan, Basta-Jovanovic, G., Radojevic-Skodric, Sanja, Velickovic, Ruzca, Chatterjee, P.K., Thiemermann, C. and Postran, Milica (2008) Acute protective effects of simvastatin in the rat model of renal ischemia-reperfusion injury: it is never too late for the pretreatment Journal of Pharmalogical Sciences, 107 (4). pp. 465-470. ISSN 1347-8613

W

Wayman, N.S., Hattori, Y., McDonald, M.C., Mota-Filipe, H., Cuzzocrea, S., Pisano, B., Chatterjee, P.K. and Thiemermann, C. (2002) Ligands of the peroxisome proliferator-activated receptors (PPAR-{gamma} and PPAR-{alpha}) reduce myocardial infarct size The FASEB Journal, 16 (9). pp. 1027-1040. ISSN 0892-6638

West, S.L., Salvage, J.P., Lobb, E.J., Armes, S.P., Billingham, N.C., Lewis, A.L., Hanlon, G.W. and Lloyd, A.W. (2004) The biocompatibility of crosslinkable copolymer coatings containing sulfobetaines and phosphobetaines Biomaterials, 25 (7-8). pp. 1195-1204. ISSN 0142-9612

Whale, R., Beacher, F., Golding, B., Gard , P.R. and Critchley, H. (2010) The acute effect of tryptophan depletion on serum neurotrophin levels (BDNF, FGF2, and S100B) in healthy subjects Psychopharmacology, 213 (2-3). pp. 651-652. ISSN 0033-3158

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Zacharowski, K., Berkels, R., Olbrich, A., Chatterjee, P.K., Cuzzocrea, S., Foster, S.J. and Thiemermann, C. (2001) The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock Critical care medicine, 29 (8). pp. 1599-1608. ISSN 1073-2322

Zacharowski, K., Chatterjee, P.K. and Thiemermann, C. (2002) Delayed preconditioning induced by lipoteichoic acid From B. Subtilis and S. Aureus is not blocked by administration of 5-Hydroxydecanoate. Shock, 17 (1). pp. 19-22. ISSN 1073-2322