Items where Author is "Hunter, A.C."

Contribution to conference proceedings in the public domain

Elsom, Jacqueline, Hunter, A.C., Lethem, Mike, Pavey, K.D. and Rees, G.D. (2002) Quartz crystal Resonant sensors in the development of biosensor technology In: GlaxoSmithKline Seminar, Weybridge. (Unpublished)

Elsom, Jacqueline, Hunter, A.C., Lethem, Mike, Pavey, K.D. and Rees, G.D. (2001) Towards a QCRS-based biosensor for monitoring interactions of microparticulates with the H376 cell line In: Quartz Crystal Resonant Sensors Conference, Brighton. (Unpublished)

Journal article

Maher, Jacqueline, Hunter, A.C., Mabley, Jon, Lippiat, J.D. and Allen, Marcus (2013) Smooth muscle relaxation and activation of the large conductance Ca++ - activated K+ (BKCa) channel by novel oestrogens British Journal of Pharmacology, 169 (5). ISSN 0007-1188

Hunter, A.C., Elsom, Jacqueline, Wibroe, Peter P. and Moghimi, S.M. (2012) Polymeric particulate technologies for oral drug delivery and targeting: A pathophysiological perspective Maturitas, 73 (1). pp. 5-18. ISSN 0378-5122

Hunter, A.C., Collins, C., Dodd, H.T., Dedi, Cynthia and Koussoroplis, S-J. (2010) Transformation of a series of saturated isomeric steroidal diols by Aspergillus tamarii KITA reveals a precise stereochemical requirement for entrance into the lactonization pathway Journal of Steroid Biochemistry and Molecular Biology , 122 (5). pp. 352-358. ISSN 1879-1220

Hamad, I., Al-Hanbali, O., Hunter, A.C., Rutt, Ken, Andresen, T.L. and Moghimi, S.M. (2010) Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere−serum interface: implications for stealth nanoparticle engineering ACS Nano, 4 (11). pp. 6629-6638. ISSN 1936-0851

Moghimi, S.M. and Hunter, A.C. (2010) Complement monitoring of carbon nanotubes Nature Nanotechnology, 5 (6). p. 382. ISSN 1748-3387

Parhamifar, L., Larsen, A.K., Hunter, A.C., Andresen, T.L. and Moghimi, S.M. (2010) Polycation cytotoxicity: a delicate matter for nucleic acid therapy-focus on polyethylenimine Soft Matter, 6 (17). pp. 4001-4009. ISSN 1744-683X

Hunter, A.C. and Moghimi, S.M. (2010) Cationic carriers of genetic material and cell death: a mitochondrial tale BBA - Biochimica et Biophysica Acta, 1797 (6-7). pp. 1203-1209. ISSN 0006-3002

Moghimi, S.M., Anderson, A.J., Hashemi, S.H., Lettiero, B., Ahmadvand, D., Hunter, A.C., Andresen, T.L., Hamad, I. and Szebeni, J. (2010) Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: the challenges ahead Journal of Controlled Release, 146 (2). pp. 175-181. ISSN 0168-3659

Moghimi, S.M. and Hunter, A.C. (2010) Letter: complement monitoring of carbon nanotubes Nature Nanotechnology, 5 (6). p. 382. ISSN 1748-3387

Hunter, A.C., Khueni-Brady, H., Barrett, P., Dodd, H.T. and Dedi, Cynthia (2010) Transformation of a series of saturated 3α-substituted 17-keto and 17a-oxa-D-homo-steroids by aspergillus tamarii KITA reveals stereochemical restriction of steroid binding orientation in the minor hydroxylation pathway The Journal of Steroid Biochemistry and Molecular Biology, 118 (3). pp. 171-176. ISSN 0960-0760

Hunter, A.C. (2009) Application of the quartz crystal microbalance to nanomedicine Journal of Biomedical Nanotechnology, 5 (6). pp. 669-675. ISSN 1550-7033

Anderson, A.J., Hashemi, S.H., Andresen, T.L., Hunter, A.C. and Moghimi, S.M. (2009) Complement: alive and kicking nanomedicines Journal of Biomedical Nanotechnology, 5 (4). pp. 364-372. ISSN 1550-7033

Hunter, A.C., Coyle, E., Morse, F., Dedi, Cynthia and Dodd, H.T. (2009) Transformation of the 5-ene steriods by the fungus aspergillus tamarii KITA: mixed molecular fate in lactonization and hydroxylation pathways with indentification of a putative 3β-hydroxy-steroid dehydrogenase/∆5-∆4 isomerase pathway The Journal of Steroid Biochemistry and Molecular Biology, 1791. pp. 110-117. ISSN 0960-0760

Hunter, A.C., Watts, K.R., Dedi, Cynthia and Dodd, H.T. (2009) An unusual ring — a opening and other reactions in steroid transformation by the thermophilic fungus Myceliophthora thermophila The Journal of Steroid Biochemistry and Molecular Biology, 116 (3-5). pp. 171-177. ISSN 0960-0760

Hamad, I., Hunter, A.C., Rutt, Ken, Liu, Z., Dai, H. and Moghimi, S.M. (2008) Complement activation by PEGylated single-walled carbon nanotubes is independent of C1q and alternative pathway turnover Molecular Immunology, 45 (14). pp. 3797-3803. ISSN 0161-5890

Elsom, Jacqueline, Lethem, Mike, Rees, G.D. and Hunter, A.C. (2008) Novel quartz crystal microbalance based biosensor for detection of oral epithelial cell-microparticulate interaction in real-time Biosensors & Bioelectronics, 23 (8). pp. 1259-1265. ISSN 0956-5663

Hunter, A.C., Mills, P.W., Dedi, Cynthia and Dodd, H.T. (2008) Predominant allyic hydroxylation at carbons 6 and 7 of 4 and 5-ene functionalized steroids by the thermophilic fungus Rhizomucor Tauricus IMI23312 Journal of Steroid Biochemistry and Molecular Biology, 180 (1-2). pp. 155-163. ISSN 0960-0760

Hamad, I., Hunter, A.C., Szebeni, J. and Moghimi, S.M. (2008) Poly(ethylene glycol)s trigger complement activation in human serum through alternative and lectin pathways: a plausible cause for anaphylaxis Molecular Immunology, 46 (2). pp. 225-232. ISSN 0161-5890

Mukhodpadhyay, R., Al-Hanbali, O., Pillai, S., Hemmersam, A.G., Meyer, R.L., Hunter, A.C., Rutt, Ken, Besenbacher, F., Moghimi, S.M. and Kingshott, P. (2007) Ordering of binary polymeric nanoparticles on hydrophobic surfaces assembled from low volume fraction dispersions Journal of the American Chemical Society, 129 (44). pp. 13390-13391. ISSN 1520-5126

Hunter, A.C. (2007) The current chemical utility of marine and terrestrial filamentous fungi in side-chain chemistry Current Organic Chemistry, 11 (8). pp. 665-677. ISSN 1385-2728

Al-Hanbali, O., Onwuzo, N.M., Rutt, Ken, Dadswell, C.M., Moghimi, S.M. and Hunter, A.C. (2007) Modification of the Stewart biphasic colorimetric assay for stable and accurate quantitatitive determination of Pluronic and Tetronic block copolymers for application in biological systems Analytical Biochemistry, 361 (2). pp. 287-293. ISSN 0003-2697

Hunter, A.C. and Bergin-Simpson, H. (2007) Distinct metabolic handling of 3β-hydroxy-17a-oxa-D-homo-5α-androstan-17-one by the filamentous fungus Apergillus tamarii KITA: evidence in support of steroid/hydroxylase binding hypothesis. BBA - Biochimica et Biophysica Acta, 1771. pp. 1254-1261.

Hunter, A.C. (2006) Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity Advanced Drug Delivery Reviews, 58 (14). pp. 1523-1531. ISSN 0169-409X

Moghimi, S.M., Hamad, I., Bunger, R., Andresen, T.L., Jorgensen, K., Hunter, A.C., Rosivall, L., Baranji, L. and Szebeni, J. (2006) Activation of the Human Complement System by cholesterol-rich and PEGylated liposomes- Modulation of cholesterol-rich liposome-mediated complement activation by elevated serum LDL and HDL levels Journal of Liposome Research, 16. pp. 167-174. ISSN 0898-2104

Al-Hanbali, O., Rutt, Ken, Sarker, Dipak, Hunter, A.C. and Moghimi, S.M. (2006) Concentration dependent structural ordering of Poloxamine 908 on polystyrene nanoparticles and their modulatory role on complement consumption Journal of Nanoscience and Nanotechnology, 6 (9). pp. 3126-3133. ISSN 1533-4880

Hunter, A.C., Elsom, Jacqueline, Ross, L. and Barrett, R. (2006) Ring-B functionalized androst-4-en-3-ones and ring-C substituted pregn-4-en-3-ones undergo differential transfonnation in Aspergillus tamarii KITA: Ring-A transformation with all C-6 substituted steroids and ring-D transfonnation with C-11 substituents Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, 1761 (3). pp. 360-366. ISSN 0167-4889

Hunter, A.C. and Priest, S.M. (2006) An efficient one-pot synthesis generating 4-ene-3,6-dione functionalised steroids from steroidal 5-en-3 beta-ols using a modified Jones oxidation methodology Steroids, 71 (1). pp. 30-33. ISSN 0039-128X

Symonds, P., Murray, J.C., Hunter, A.C., Debska, G., Szewczyk, A. and Moghimi, S.M. (2005) Low and high molecular weight poly(l-lysine)s/poly(l-lysine)–DNA complexes initiate mitochondrial-mediated apoptosis differently Febs Letters, 579 (27). pp. 6191-6198. ISSN 0014-5793

Moghimi, S.M., Symonds, P., Murray, J.C., Hunter, A.C., Debska, G. and Szewczyk, A. (2005) A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy Molecular Therapy, 11 (6). pp. 990-995. ISSN 1525-0024

Hunter, A.C., Kennedy, S., Clabby, S.J. and Elsom, Jacqueline (2005) Fate of novel Quasi reverse steroidal substrates by Aspergillus tamarii KITA: bypass of lactonisation and an exclusive role for the minor hydroxylation pathway Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 1734 (2). pp. 190-197. ISSN 1388-1981

Moghimi, S.M., Hunter, A.C. and Murray, J.C. (2005) Nanomedicine: current status and future prospects FASEB Journal, 19 (3). pp. 311-330. ISSN 1530-6860

Moghimi, S.M., Hunter, A.C., Dadswell, C.M., Savay, S., Alving, C.R. and Szebeni, J. (2004) Causative factors behind poloxamer 188 (Pluronic F68, Flocor™)-induced complement activation in human sera A protective role against poloxamer-mediated complement activation by elevated serum lipoprotein levels Biochimica et biophysica acta (BBA) - molecular basis of disease, 1689 (2). pp. 103-113. ISSN 0925-4439

Kiran, I., Hanson, J.R. and Hunter, A.C. (2004) The microbiological hydroxylation of some methoxysteroids by Cephalosporium aphidicola Journal of Chemical Research, 2004 (5). pp. 362-363. ISSN 0308-2342

Moghimi, S.M., Hunter, A.C., Murray, J.C. and Szewczyk, A. (2004) Cellular distribution of nonionic micelles Science, 303 (5658). pp. 626-628. ISSN 1095-9203

Hunter, A.C. and Carragher, N.E. (2003) Flexibility of the endogenous progesterone lactonisation pathway in Aspergillus tamarii KITA: transformation of a series of cortical steroid analogues The Journal of Steroid Biochemistry and Molecular Biology, 87 (4-5). pp. 301-308. ISSN 0960-0760

Pavey, K.D., Hunter, A.C. and Paul, F. (2003) Real-time evaluation of macromolecular surface modified quartz crystal resonant sensors under cryogenic stress for biological applications Biosensors and Bioelectronics, 18 (11). pp. 1349-1354. ISSN 0956-5663

Moghimi, S.M., Pavey, K.D. and Hunter, A.C. (2003) Real-time evidence of surface modification at polystyrene lattices by poloxamine 908 in the presence of serum: in vivo conversion of macrophage-prone nanoparticles to stealth entities by poloxamine 908 Febs letters, 547 (3). pp. 177-182. ISSN 0014-5793

Hanson, J.R. and Hunter, A.C. (2003) The microbiological hydroxylation of 3alpha,17beta- and 3beta,l7alpha-dihydroxy-5alpha-androstanes by Cephalosporium aphidicola Journal of chemical research, 2003 (4). pp. 216-217. ISSN 0308-2342

Hunter, A.C. and Moghimi, S.M. (2003) Synthetic polymers in 21st century therapeutics: the way forward Drug Discovery Today, 8 (4). pp. 154-156. ISSN 1359-6446

Gbadamosi, J.K., Hunter, A.C. and Moghimi, S.M. (2002) PEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance FEBS Letters, 532 (3). pp. 338-344. ISSN 0014-5793

Hunter, A.C. and Moghimi, S.M. (2002) Therapeutic synthetic polymers: a game of Russian roulette? Drug Discovery Today, 7 (19). pp. 998-1001. ISSN 1359-6446

Dick, G.M., Hunter, A.C. and Sanders, K.M. (2002) Ethylbromide Tamoxifen, a membrane-impermeant antiestrogen, activates smooth muscle calcium-activated large-conductance Potassium channels from the extracellular side Molecular Pharmacology, 61 (5). pp. 1105-1113. ISSN 1521-0111

Moghimi, S.M., Hunter, A.C. and Murray, J.C. (2001) Long-circulating and target-specific nanoparticles: theory to practice Pharmacological Reviews, 53 (2). pp. 283-318. ISSN 1521-0081

Moghimi, S.M. and Hunter, A.C. (2001) Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups Pharmaceutical research, 18 (1). pp. 1-8. ISSN 0724-8741

Moghimi, S.M. and Hunter, A.C. (2001) Capture of stealth nanoparticles by the body’s defences Critical reviews in therapeutic drug carrier systems, 18 (6). pp. 527-550. ISSN 0743-4863

Sahebgharani, M., Hardy, S.P., Lloyd, Andrew, Hunter, A.C. and Allen, Marcus (2001) Volume-activated chloride currents in HeLa cells are blocked by Tamoxifen but not by a membrane impermeant quaternary analogue Cellular Physiology and Biochemistry, 11 (2). pp. 99-104. ISSN 1421-9778

Meikle, Steve, Hunter, A.C., Steward, C., Ampilozous, E. and Lloyd, Andrew (1999) The synthesis and evaluation of poly (carboxybetaines) as novel anti-adherent biomaterials Artificial Organs, 23 (7). p. 635.