Adsorbed pluronics on the skin of human volunteers: effects on bacterial adhesion

Marsh, L.H., Alexander, C., Coke, M., Dettmar, P.W., Havler, M., Nevell, T.G., Smart, J.D., Timmins, B. and Tsibouklis, J. (2003) Adsorbed pluronics on the skin of human volunteers: effects on bacterial adhesion International Journal of Pharmaceutics, 251 (1-2). pp. 155-163.

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Abstract

An amphiphilic copolymer, Pluronic F127, has been deposited, by adsorption, to the skin of human volunteers and the ability of the coated skin to resist bacterial colonisation has been evaluated. In parallel, the ability of the same copolymer to act as a bacterial release agent has been evaluated. In both cases, F127 proved to be of little added value in formulations designed to suppress the bacterial colonisation of human skin.

Item Type: Journal article
Uncontrolled Keywords: Bacterial-release coatings; Pluronic F127; In vivo evaluation
Subjects: B000 Health Professions > B200 Pharmacology Toxicology and Pharmacy > B240 Pharmaceutics
DOI (a stable link to the resource): 10.1016/S0378-5173(02)00592-6
Faculties: Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences
Depositing User: editor spbs
Date Deposited: 01 Dec 2006
Last Modified: 11 Jun 2013 12:36
URI: http://eprints.brighton.ac.uk/id/eprint/966

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