Overall, A.D.J., Byrne, K.A., Pilkington, J.G. and Pemberton, J.M. (2005) Heterozygosity, inbreeding and neonatal traits in Soay sheep on St Kilda Molecular Ecology, 14 (11). pp. 3383-3393. ISSN 1365-294XFull text not available from this repository.
We investigated whether birth weight and neonatal survival, a period within which 24% of all mortalities occur, were correlated with levels of inbreeding in St Kilda Soay sheep, using pedigree inbreeding coefficients and four marker-based estimators of inbreeding. None of the inbreeding estimators, either of the offspring, or of their mothers, explained significant variation in a lamb's birth weight or probability of surviving the neonatal period, suggesting low inbreeding depression for these traits. We evaluated the correlation between the marker-based measures of inbreeding and inbreeding coefficients obtained from the Soay pedigree, where paternal links were inferred using the same panel of microsatellite markers. Even when using a relatively complete portion of the pedigree, in which all individuals had known maternal and paternal grandparents, the correlation was found to be weak (r = −0.207, where mean f = 0.0168). These results add support to the recent prediction that when the mean and variance in inbreeding are low in a population, heterozygosity–fitness correlations can be very weak or even undetectable. The pursuit of more detailed pedigrees offers the best prospect for identifying inbreeding depression within this study population.
|Item Type:||Journal article|
|Uncontrolled Keywords:||birth weight; heterozygosity–fitness correlation; inbreeding depression; microsatellite; neonatal survival; Soay sheep|
|Subjects:||C000 Biological and Biomedical Sciences > C400 Genetics|
|DOI (a stable link to the resource):||10.1111/j.1365-294X.2005.02682.x|
|Faculties:||Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences|
|Depositing User:||editor spbs|
|Date Deposited:||08 Nov 2007|
|Last Modified:||11 Jun 2013 09:49|
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