Evidence for a sustained increase in clonal beta-cell basal intracellular Ca2+ levels after incubation in the presence of newly diagnosed Type-1 diabetic patient sera. Possible role in serum-induced inhibition of insulin secretion

Abstract

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ncluded in the incubation medium. Type-1 diabetic patient sera significantly (P<
                                                                               ^
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e early complement components C1q and C3 resulted in a significant reduction (P<
                                                                               ^
	XML::LibXML::parse_string('XML::LibXML=HASH(0x2af1ffe98630)', '<fragment>We have previously reported that newly diagnosed Ty...') called at /home/eprints3/perl_lib/EPrints/XML/LibXML.pm line 106
	EPrints::XML::parse_xml_string('<fragment>We have previously reported that newly diagnosed Ty...') called at /home/eprints3/perl_lib/EPrints/Extras.pm line 85
	eval {...} called at /home/eprints3/perl_lib/EPrints/Extras.pm line 85
	EPrints::Extras::render_xhtml_field('EPrints::Session=HASH(0x2af1f27bc330)', 'EPrints::MetaField::Longtext=HASH(0x2af200443dc0)', 'We have previously reported that newly diagnosed Type-1 diabe...', 'undef', 'undef', 'EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)') called at /home/eprints3/perl_lib/EPrints/MetaField.pm line 960
	EPrints::MetaField::call_property('EPrints::MetaField::Longtext=HASH(0x2af200443dc0)', 'render_value', 'EPrints::Session=HASH(0x2af1f27bc330)', 'EPrints::MetaField::Longtext=HASH(0x2af200443dc0)', 'We have previously reported that newly diagnosed Type-1 diabe...', 'undef', 'undef', 'EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)') called at /home/eprints3/perl_lib/EPrints/MetaField.pm line 622
	EPrints::MetaField::render_value('EPrints::MetaField::Longtext=HASH(0x2af200443dc0)', 'EPrints::Session=HASH(0x2af1f27bc330)', 'We have previously reported that newly diagnosed Type-1 diabe...', 'undef', 'undef', 'EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)') called at /home/eprints3/perl_lib/EPrints/DataObj.pm line 759
	EPrints::DataObj::render_value('EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)', 'abstract') called at /home/eprints3/archives/brighton/cfg/cfg.d/eprint_render.pl line 182
	EPrints::Config::brighton::__ANON__('EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)', 'EPrints::Session=HASH(0x2af1f27bc330)', 'undef') called at /home/eprints3/perl_lib/EPrints/Repository.pm line 1170
	eval {...} called at /home/eprints3/perl_lib/EPrints/Repository.pm line 1170
	EPrints::Repository::call('EPrints::Repository=HASH(0x2af1ff88dc80)', 'eprint_render', 'EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)', 'EPrints::Session=HASH(0x2af1f27bc330)', 'undef') called at /home/eprints3/perl_lib/EPrints/DataObj/EPrint.pm line 1717
	EPrints::DataObj::EPrint::render('EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)') called at /home/eprints3/perl_lib/EPrints/DataObj/EPrint.pm line 1564
	EPrints::DataObj::EPrint::generate_static('EPrints::DataObj::EPrint=HASH(0x2af1f2726a00)') called at /home/eprints3/perl_lib/EPrints/Update/Abstract.pm line 85
	EPrints::Update::Abstract::update('EPrints::Repository=HASH(0x2af1ff88dc80)', 'en', 575, '/archive/00/00/05/75/') called at /home/eprints3/perl_lib/EPrints/Apache/Rewrite.pm line 210
	EPrints::Apache::Rewrite::handler('Apache2::RequestRec=SCALAR(0x2af1f272e680)') called at -e line 0
	eval {...} called at -e line 0