Plantar skin in type II diabetes: an investigation of protein glycation and biomechanical properties of plantar epidermis

Hashmi, F., Malone-Lee, J. and Hounsell, L. (2006) Plantar skin in type II diabetes: an investigation of protein glycation and biomechanical properties of plantar epidermis European journal of dermatology, 16 (1). pp. 23-32. ISSN 1167-1122

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Abstract

Summary : Gluten sensitivity with or without coeliac disease (CD) symptoms and intestinal pathology has been suggested as a potentially treatable cause of various diseases. CD is a chronic disease which improves on withdrawal of wheat gliadins and barley, rye and oat prolamins from the diet. There have been numerous reports linking CD with several skin conditions. A body of evidence shows that dermatitis herpetiformis is actually a cutaneous manifestation of CD. Autoimmune diseases, allergic diseases, psoriasis and miscellaneous diseases have also been described with gluten intolerance. Dermatologists should be familiar with the appraisal of gluten sensitive enteropathy and should be able to search for an underlying gluten intolerance (GI). Serological screening by means of antigliadin, antiendomysial and transglutaminase antibodies should be performed. HLA typing is often useful in association with serologic tests. Intestinal biopsy is usually needed to establish the diagnosis of CD or GI. Thus, gluten intolerance gives rise to a variety of dermatological manifestations which may benefit from a gluten-free diet.

Item Type: Journal article
Uncontrolled Keywords: coeliac disease, dermatitis herpetiformis, gluten free-diet, gluten intolerance
Subjects: B000 Health Professions
Faculties: Faculty of Health and Social Sciences > School of Health Professions
Depositing User: editor health
Date Deposited: 04 Sep 2007
Last Modified: 18 Jun 2010 11:28
URI: http://eprints.brighton.ac.uk/id/eprint/557

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