Caudwell Xtreme Everest: a field study of human adaptation to hypoxia

Grocott, M., Richardson, A., Montgomery, H. and Mythen, M. (2007) Caudwell Xtreme Everest: a field study of human adaptation to hypoxia Critical Care, 11 (4). p. 151. ISSN 1364-8535

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Abstract

Caudwell Xtreme Everest (CXE) is a large healthy volunteer field study investigating human adaptation to environmental hypoxia. More than 200 individuals were studied at sea-level and in four laboratories on the trek to Everest Base Camp (5,300 m). Fifteen physicians climbed high on Everest and continued the studies as they ascended; eight of these individuals reached the summit of Everest and succeeded in sampling arterial blood at 8,400 m on their descent. Core measurements included cardiopulmonary exercise testing, neuropsychological assessment, near infra-red spectroscopy of brain and exercising muscle, blood markers and daily recording of simple physiological variables. The goal of CXE is to further our understanding of human adaptation to cellular hypoxia, a fundamental mechanism of injury in critical illness, with the aim of improving the care of critically ill patients.

Item Type: Journal article
Uncontrolled Keywords: hypoxia; human adaptation; care of patients
Subjects: C000 Biological and Biomedical Sciences > C600 Sport and Exercise Science
B000 Health Professions > B100 Anatomy Physiology and Pathology > B190 Anatomy, Physiology and Pathology not elsewhere classified
B000 Health Professions > B100 Anatomy Physiology and Pathology > B120 Physiology
B000 Health Professions > B100 Anatomy Physiology and Pathology > B110 Anatomy
DOI (a stable link to the resource): 10.1186/cc5921
Faculties: Faculty of Education and Sport > Chelsea School
Depositing User: Chelsea editor
Date Deposited: 16 Dec 2008
Last Modified: 19 Jul 2013 12:48
URI: http://eprints.brighton.ac.uk/id/eprint/5328

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