Recent developments in polymeric nanoparticle engineering and their applications in experimental and clinical oncology

Moghimi, S.M (2006) Recent developments in polymeric nanoparticle engineering and their applications in experimental and clinical oncology Anticancer agents in medicinal chemistry, 6 (6). pp. 553-561. ISSN 1871-5206

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Abstract

Promising results have come from attempts to direct drugs, nucleic acids and diagnostic agents to tumours by using polymeric nanoparticles. Such carriers are versatile; their encapsulation capacity, drug release profile, and biological performance vary with their chemical makeup, morphology, and size. Polymeric nanoparticles may therefore be engineered for therapeutic and diagnostic purposes in accordance with the type, developmental stage and location of the cancer as well as the required route of administration. This article examines recent developments in design and engineering of polymeric nanoparticles and related platforms to include supramolecular systems such as nanocapsules and nanoparticle-based hydrogels, and assesses their potential diagnostic and therapeutic applications in experimental and clinical oncology.

Item Type: Journal article
Subjects: F000 Physical Sciences > F100 Chemistry
Faculties: Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences > Chemical Biology
Depositing User: editor spbs
Date Deposited: 08 Nov 2007
Last Modified: 18 Jun 2010 11:33
URI: http://eprints.brighton.ac.uk/id/eprint/2778

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