Epidemiology and ecology of enterococci, with special reference to antibiotic resistant strains, in animals, humans and the environment. Example of an ongoing project within the European research programme

Kühn, I, Iversen, A, Burman, L.G., Olsson-Liljequist, B., Franklin, A., Finn, M., Aarestrup, F., Seyfarth, A.M., Blanch, A.R., Taylor, H., Caplin, J.L., Moreno, M.A., Dominguez, L. and Möllby, R. (2000) Epidemiology and ecology of enterococci, with special reference to antibiotic resistant strains, in animals, humans and the environment. Example of an ongoing project within the European research programme International Journal of Antimicrobial Agents, 14 (4). pp. 337-342. ISSN 0924-8579

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Abstract

The objectives of the present study are to generate knowledge of the ecology and epidemiology of enterococci in the food chain by studying the following: (1) the population structure (in measures of abundance, number of vancomycin resistant strains,antibiotic resistance patterns, diversity, and stability) among enterococcal populations in different geographical regions and in different links of the food chain (2) possible transmission of strains through the food chain and between hospital environments and the food chain (3) the association between vancomycin resistance and individual strains of enterococci and (4) the diversity of the drug resistance genes in enterococci. So far, 1578 samples have been collected from different countries within the EU (Sweden, Denmark, UK and Spain), and from different habitats (pig farms, carcasses in slaughter houses, soil, manure, water, sewage, and humans). Total and vancomycin resistant enterococcal populations in each sample have been enumerated and more than 12 000 isolates have been characterised by phenotyping. Representative isolates are further species identified and characterised by genotyping and MIC determination and from antibiotic resistant isolates the resistance genes are characterised.

Item Type: Journal article
Uncontrolled Keywords: Enterococcus; Antibiotic resistance; Vancomycin; Ecology; Epidemiology
Subjects: C000 Biological and Biomedical Sciences > C500 Microbiology
Faculties: Faculty of Science and Engineering > School of Environment and Technology
Faculty of Science and Engineering > School of Environment and Technology > Ecology, Landscape and Pollution Management
Depositing User: Dr Jonathan Caplin
Date Deposited: 09 Aug 2007
Last Modified: 09 May 2012 12:47
URI: http://eprints.brighton.ac.uk/id/eprint/2158

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