Riley, R.G., Green, K.L., Smart, John, Tsibouklis, J., Davis, J.A., Hampson, F., Dettmar, P.W. and Wilber, W.R. (2001) The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study Biomaterials, 22 (13). pp. 1861-1867. ISSN 0142-9612Full text not available from this repository.
The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.
|Item Type:||Journal article|
|Uncontrolled Keywords:||14C-poly(acrylic acid); In vivo; Polymer retention; Mucoadhesion|
|Subjects:||C000 Biological and Biomedical Sciences|
|DOI (a stable link to the resource):||10.1016/S0142-9612(00)00369-0|
|Faculties:||Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences > Biomedical Materials
Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences
|Depositing User:||editor spbs|
|Date Deposited:||01 Dec 2006|
|Last Modified:||20 Apr 2015 08:47|
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