The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study

Riley, R.G., Green, K.L., Smart, J.D., Tsibouklis, J., Davis, J.A., Hampson, F., Dettmar, P.W. and Wilber, W.R. (2001) The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study Biomaterials, 22 (13). pp. 1861-1867. ISSN 0142-9612

Full text not available from this repository.

Abstract

The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.

Item Type: Journal article
Uncontrolled Keywords: 14C-poly(acrylic acid); In vivo; Polymer retention; Mucoadhesion
Subjects: C000 Biological and Biomedical Sciences
DOI (a stable link to the resource): 10.1016/S0142-9612(00)00369-0
Faculties: Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences > Biomedical Materials
Faculty of Science and Engineering > School of Pharmacy and Biomolecular Sciences
Depositing User: editor spbs
Date Deposited: 01 Dec 2006
Last Modified: 24 Oct 2013 09:08
URI: http://eprints.brighton.ac.uk/id/eprint/1031

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year